Download Computational pharmaceutics : application of molecular by Defang Ouyang, Sean C. Smith PDF

By Defang Ouyang, Sean C. Smith

Molecular modeling strategies were normal in drug discovery fields for rational drug layout and compound screening. Now those thoughts  are used to version or mimic the habit of molecules, and support us learn formula on the molecular point. Computational pharmaceutics allows us to appreciate the mechanism of drug supply, and to increase new drug supply systems.

The publication discusses the modeling of other drug supply structures, together with cyclodextrins, reliable dispersions, polymorphism prediction, dendrimer-based supply structures, surfactant-based micelle, polymeric drug supply platforms, liposome, protein/peptide formulations, non-viral gene supply platforms, drug-protein binding, silica nanoparticles, carbon nanotube-based drug supply platforms, diamond nanoparticles and layered double hydroxides (LDHs) drug supply systems.

Although there are various current books approximately rational drug layout with molecular modeling recommendations, those strategies nonetheless glance mysterious and daunting for pharmaceutical scientists. This publication fills the distance among pharmaceutics and molecular modeling, and provides a scientific and total advent to computational pharmaceutics. It covers all introductory, complicated and professional degrees. It presents a wholly diversified standpoint to pharmaceutical scientists, and should significantly facilitate the advance of pharmaceutics. It additionally is helping computational chemists to seem for the real questions within the drug supply field.

This ebook is integrated within the Advances in Pharmaceutical Technology e-book series.

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And Kendrick, J. (2008) A major advance in crystal structure prediction. Angewandte Chemie International Edition, 47 (13), 2427–2430. , et al. (2011) Successful prediction of a model pharmaceutical in the fifth blind test of crystal structure prediction. International Journal of Pharmaceutics, 418 (2), 168–178. , et al. (2013) Complex polymorphic system of gallic acid‐five monohydrates, three anhydrates, and over 20 solvates. Crystal Growth and Design, 13 (1), 19–23. , et al. 1]nonane‐2,4‐dione.

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