By Anil Kumar Verma, V. K. Gupta
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Antiinflammatory actions of cat's claw: the role of NF-kappaB. Alimentary Pharmacology & Therapeutics, 12: 1279-1289. , Tho, Y. and Hashizume, N. (2007). Beneficial effects of grape seed extract on malondialdehyde-modified LDL. Journal of Nutritional Science and Vitaminology (Tokyo), 53: 174-182. S. J. (1997). A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative StUdy. New England Journal of Medicme, 336: 1216-1222.
Inflammation Research, 50: 442-448. C. P. (1996). Facts and theories concerning the mechanisms of carcinogenesis. FASEB Journal, 5: 2280-2288. L. M. (2007). Platelet reactivity in male smokers following the acute consumption of a flavanol-rich grapeseed extract. Journal of Medicmal Food, 10: 725-730. , Niestroj, 1. and Sies, H. (2001). Profiles of antioxidants in human plasma. Free Radical Biology & Medicine, 30: 456-462. J. E. (1995). Altered antioxidant status and increased lipid peroxidation in children with cystic fibrosis.
Only one antioxidant product (Ebselen, an organic selenium salt) showed a significant effect both as neuroprotector (prophylactic) and to improve patient recovery within the next 24 h of brain infact, and follow-up oral administration during the next 30 days. The main recommendation was the future use of an antioxidant cocktail instead of a single antioxidant, with a high probability of synergic effects, which would be the case of ANPs considering that they contain a crude extract of natural origin with several components, some of them antioxidants.